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Symbol Name ID |
Brca1
breast cancer 1, early onset MGI:104537 |
| Darker colors indicate more annotations |
| Human Phenotypes | Diabetes mellitus |
Exocrine pancreatic insufficiency |
Pancreatic adenocarcinoma |
Abnormality of the hypothalamus-pituitary axis |
Hypogonadism |
| Disease(s) Associated with BRCA1 | |||||
| Fanconi anemia | |||||
| pancreatic cancer |
| Mouse Phenotypes | decreased mammary gland epithelial cell proliferation |
increased mammary gland epithelial cell proliferation |
increased salivary adenocarcinoma incidence |
decreased thymocyte number |
abnormal mammary gland development |
abnormal branching of the mammary ductal tree |
abnormal involution of the mammary gland |
abnormal mammary gland growth during pregnancy |
abnormal mammary gland duct morphology |
abnormal mammary gland lobule morphology |
mammary gland alveolar hyperplasia |
increased mammary gland tumor incidence |
increased mammary adenocarcinoma incidence |
mammary gland hyperplasia |
abnormal ovary morphology |
ovary cyst |
small testis |
increased T cell derived lymphoma incidence |
increased mammary gland apoptosis |
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| Availability | Mouse Genotype | |||||||||||||||||||
| Brca1tm2Arge/Brca1tm2Arge | ||||||||||||||||||||
| Brca1tm3.1Rjbr/Brca1tm3.1Rjbr | ||||||||||||||||||||
| Brca1tm5.1Cxd/Brca1tm5.1Cxd | ||||||||||||||||||||
| Brca1tm1Bhk/Brca1+ | ||||||||||||||||||||
| Brca1tm1Aash/Brca1tm1Aash Tg(LGB-cre)74Acl/0 (conditional) |
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| Brca1tm1Brn/Brca1tm1Brn (conditional) | ||||||||||||||||||||
| Brca1tm1Thl/Brca1tm1Thl Waptm1(cre)Arge/0 (conditional) |
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| Brca1tm2Cxd/Brca1tm2Cxd Tg(Fshr-cre)1Ldu/0 (conditional) |
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| Brca1tm2Cxd/Brca1tm2Cxd Tg(MMTV-cre)4Mam/0 (conditional) |
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| Brca1tm2Mak/Brca1tm2Mak Tg(Lck-cre)548Jxm/? (conditional) |
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| Brca1tm2Mak/Brca1tm2Mak Tg(Wap-cre)11738Mam/? (conditional) |
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| Brca1tm1Arge/Brca1tm1Thl Waptm1(cre)Arge/0 (conditional) |
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| Brca1tm1Cxd/Brca1tm2Cxd Tg(Wap-cre)11738Mam/0 (conditional) |
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| Brca1tm1Cxd/Brca1tm2Cxd Tg(MMTV-cre)4Mam/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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